Medications Commonly Used to Augment Ketamine Infusions

If you’ve tried multiple strategies for treating depression, anxiety, PTSD, or chronic pain, you may feel like there’s no stone left unturned. However, there’s still hope: ketamine infusion has shown promising results for many individuals struggling with treatment-resistant depression and a plethora of other conditions. If you’re interested in working with a medical professional who can administer ketamine infusions, your doctor may use other medications to augment the effect of ketamine. Here, we share more about the medications that are commonly used in conjunction with ketamine treatment.


When you receive your ketamine infusions, magnesium may be added into the treatment plan. Magnesium is a mineral that we all require, as it plays several important roles within the body. Studies suggest that magnesium can benefit mental health by improving the connections between neurons. When appropriate, we use magnesium in combination with ketamine infusions to enhance the treatment.


Scopolamine is part of the anticholinergics family, meaning it works on the central nervous system to calm the muscles in the stomach and bowels. Although scopolamine is commonly given in patch form as an anti-nausea medication, this drug has been shown to have positive effects for individuals with treatment-resistant depression. As a result, we often combine scopolamine with ketamine infusions.

Nicotinamide Adenine Dinucleotide (NAD)

Nicotinamide adenine dinucleotide (NAD) is a coenzyme that is naturally present within our bodies. It’s involved in numerous functions within the body and is sometimes used as a therapy to augment ketamine. When NAD is combined with your ketamine infusion, it may be helpful in boosting the results of the treatment. NAD is especially helpful for treating individuals struggling with addiction, as the combination of ketamine and NAD is often effective at reducing withdrawal symptoms and memories associated with substance abuse.

If you’re searching for a new solution for your depression, anxiety, PTSD, or other condition, ketamine infusion may be the remedy. Our clinic was founded by two physicians who have firsthand experience with the positive effects of ketamine treatment for individuals who’ve tried everything else. To improve your experience, the medications mentioned here are options to include with your infusion. Ready to learn more about the process and find out if you’re a candidate for this treatment? Please contact us today so we can chat about your symptoms and medical history. We’d love to help you find relief through ketamine infusions in our calm, soothing environment.

Further Reading

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